IgnoreRegistry in combination with DisappearItems: In my guixt.ini file I use "IgnoreRegistry Yes". In addition I'd like to use the option "DisappearItems " with "Activate GuiXT" in WIndows Registry. Will this work?

Yes, the "DisappearItems" option in Windows Registry is evaluated by SAP GUI and is not effected by "IgnoreRegistry" in guixt.ini.